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“TIME TO STEP YOUR GAME UP” ” Olivia…….this late…….got distracted on her way….to Grandmother’s house…… A wolf in lamb clothing came….blew her mind…and changed her ways…now she’s turned out……lost and turned out…….she’s lost and turned out”……”(Olivia) Lost and Turned Out”….The Whispers It’s 2017…..Men in prison must now step their game up….meaning their mental,…spiritual and potential […]
Resiniferatoxin is toxic and can inflict a chemical burning sensation in microscopic quantities. The primary action of resiniferatoxin is to activate sensory neurons responsible for the perception of pain. It is currently the most potent TRPV1 agonist known, with ~500x higher binding affinity for TRPV1 than capsaicin , the active ingredient in hot chili peppers such as those produced by Capsicum annuum . Animal experiments suggest that, in humans, ingestion of 10 g may be fatal or cause serious damage to health.  It causes severe burning pain in sub-microgram (less than 1/1,000,000th of a gram) quantities when ingested orally.