Another approach to treatment of small areas of vitiligo is the use of topical creams . These include corticosteroid creams or the topical immunomodulator, tacrolimus. Using medium and high strength topical corticosteroids for 1-4 months has been found to be the most effective and safest therapy for localized vitiligo. Steroid injections have also been used for the treatment of vitiligo. Steroids can be used twice daily for limited periods of time. Repigmentation of the vitiliginous area with topical corticosteroids is most likely to occur on hair bearing areas of the skin. However, corticosteroids should not be used for long periods of time, since they may lead to thinning of the skin, growth of blood vessels, and rashes.