Receptores intracelulares esteroides

GPCR activation can evoke signal pathways that do not require coupling to G proteins. Much as activated receptor conformations are recognized by their complementary G proteins (the classical route), so too they can be recognized by other signaling proteins including the GRKs, arrestins, JAK, Src family kinases, and PDZ-domain containing proteins (non-classical signaling, Sun et al., 2007). Such coupling can evoke clathrin-mediated internalization, activation of MAP (mitogen-activated protein) kinase signaling, or stimulation of Na + /H + exchange.

Receptores intracelulares esteroides

receptores intracelulares esteroides

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receptores intracelulares esteroidesreceptores intracelulares esteroidesreceptores intracelulares esteroidesreceptores intracelulares esteroidesreceptores intracelulares esteroides

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