Many treatments have been advocated to help minimize the symptoms of CRF (also called the uremic syndrome). None of them can cure the problem, and not all of them have proven to work, so it is important that we tailor make each pet’s therapy to its individual needs. In addition, indiscriminate use of medication to treat a perceived problem can make the kidney disease worse. This applies to almost every drug, since the kidneys are so intimatley invovled in the metabolism of drugs. The medical axiom of “first do no harm” applies directy to kidney disease.